Thursday, February 10, 2011

Nifedipine less effective than terbutaline to aid external cephalic version

While nifedipine mainly used as a great antianginal and antihypertensive with its advantages and side effects, some suggestion also indicated this realtor for preterm delivery.

However, based about current systematic review of three clinical studies that all required women with an individual fetus in phrase breech or transverse presentation, compared along with terbutaline (a betamimetic), using the calcium antagonist Procardia as anti-contraction medications appear less effective in facilitating external cephalic version.

In accordance with current researchers, their own finding were astonishing, because from studies in this area, nifedipine had shown for the usefulness, positive impact about perinatal outcomes, and also reduced adverse effects when compared to terbutaline.

Despite several possibly limitation with the study included 2 of the studies used terbutaline (therefore it will be unclear if the findings can end up being generalized to all betamimetics) and supplementary trial outcomes are not amenable to put analysis and nifedipine and terbutaline doses differed in both trials, published in BJOG on 12 , 24, 2010, in line with the researchers from Australia, their review identified “no evidence to aid the use of nifedipine for tocolysis to aid external cephalic model.”

In addition, in contrast to placebo, minor unwanted effects of nifedipine make use of were slightly more than terbutaline.

No comments:

Post a Comment